Clinical Research Studies for
Pediatric Migraine

About
the Studies

The PIONEER-PEDS1, REBUILD-1, and REBUILD-2 Studies are evaluating the safety and efficacy of several study treatments to potentially prevent or treat migraines in children and teens.

Learn more about the studies in this video:

PIONEER-PEDS1

The PIONEER-PEDS1 Study is evaluating the safety and efficacy of a study treatment for children and teens with migraines. Your child may be eligible to participate if they:

The PIONEER-PEDS1 Study includes up to 4 study visits over the course of up to 18 weeks. Those who qualify and meet all other eligibility criteria will receive either the study treatment or a placebo (a substance that looks like the study treatment but has no active ingredients) administered as an oral tablet and will record their symptoms in a study diary. Participants may be compensated for travel and expenses.

REBUILD-1

The REBUILD-1 Study is evaluating the safety and efficacy of a study treatment for children and teens with episodic migraines, meaning fewer than 14 headache days per month. Your child may be eligible to participate if they:

The REBUILD-1 Study includes up to 18 study visits over the course of up to 18 months. Those who qualify and meet all other eligibility criteria will receive either the study treatment or a placebo (a substance that looks like the study treatment but has no active ingredients) administered as a subcutaneous injection (under the skin) and will record their symptoms in a study diary. Participants may be compensated for travel and expenses.

REBUILD-2

The REBUILD-2 Study is evaluating the safety and efficacy of a study treatment for children and teens with chronic migraines, meaning more than 15 headache days per month. Your child may be eligible to participate if they:

The REBUILD-2 Study includes up to 18 study visits over the course of up to 18 months. Those who qualify and meet all other eligibility criteria will receive either the study treatment or a placebo (a substance that looks like the study treatment but has no active ingredients) administered as a subcutaneous injection (under the skin) and will record their symptoms in a study diary. Participants may be compensated for travel and expenses.

Your choice regarding cookies on this site -

We use cookies to optimize site functionality and give you the best experience. Necessary cookies enable core functionality. The website cannot function properly without these cookies and can only be disabled by changing your browser preferences.

For more detailed information on the cookies we use, please check our Privacy Policy.

By continuing to access this website, you are giving us consent to collect cookies.